one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity associated with bortezomib, a proteasome inhibitor Utilized in the cure of various myeloma. Its synthesis or analyze is important for guaranteeing the purity and safety of your drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen output.
Imatinib Intermediate (CAS NO. 152460-10-1): A important compound in the synthesis of imatinib, a drug that targets precise forms of most cancers, together with Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats a variety of cancers like breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are intermediates in the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the creation procedure and guaranteeing large purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is utilized to take care of breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is undoubtedly an estrogen receptor antagonist Employed in the procedure of breast most cancers. Several intermediates assist in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug effective in managing cancers including ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the remedy of colorectal most cancers and little mobile lung most cancers.
three-Amino-1-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, which have numerous programs, like antiviral Attributes.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-four to control blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with 1 the synthesis of various gluconic acid derivatives, that happen to be Utilized in food items, pharmaceutical, and industrial applications.
Canagliflozin Intermediate 2: A precursor within the 3-(4-Nitro-1-oxo-1 synthesis of canagliflozin, a medication utilized to handle sort 2 diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).